• People with moderately to severely compromised immune systems are especially vulnerable to COVID-19, and may not build the same level of immunity to 2-dose vaccine series compared to people who are not immunocompromised.

• CDC recommends that people with moderately to severely compromised immune systems receive an additional dose of mRNA COVID-19 vaccine at least 28 days after a second dose of Pfizer-BioNTech COVID-19 vaccine or Moderna COVID-19 Vaccine.

• This additional dose is intended to improve immunocompromised people’s response to their initial vaccine series

• This includes people who:​

 

• Are receiving active cancer treatment for tumors or cancers of the bloodReceived an organ transplant and are taking medicine to suppress the immune system

• Received a stem cell transplant within the last 2 years or are taking medicine to suppress the immune system

• Have moderate or severe primary immunodeficiency (such as DiGeorge syndrome, Wiskott-Aldrich syndrome)

• Have advanced or untreated HIV infection

• Are receiving active treatment with high-dose corticosteroids or other drugs that may suppress your immune response

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